Cytokines & Growth Factors as Predictors of Response to Medical Treatment in Diabetic Macular Edema

Article Name: Cytokines and Growth Factors as Predictors of Response to Medical Treatment in Diabetic Macular Edema

What are the takeaway points from this article?

The first line treatment for those with diabetic macular edema is anti-vascular endothelial growth factors (anti-VEGF). However, some cases do not respond to anti-VEGF intravitreal injections. Steroids may also be used as an alternative to anti-VEGF therapies. Cytokine levels change after treatment, suggesting that cytokines other than VEGF are also implicated in DME. More research is needed to determine which cytokines are related to DME severity, predictors of response to treatment, and how this can guide therapy.

Reference:

Torres-Costa S, Alves Valente MC, Falcão-Reis F, Falcão M. Cytokines and Growth Factors as Predictors of Response to Medical Treatment in Diabetic Macular Edema. J Pharmacol Exp Ther. 2020. Available from: https://pubmed.ncbi.nlm.nih.gov/32245883/

Date Published: April 3, 2020

Summary by: Sarah Yeo